Witwer, K.W.; et al. Correction: miRNA Profiles of Monocyte-Lineage Cells Are Consistent with Complicated Roles in HIV-1 Restriction. Viruses 2012, 4, 1844-1864
نویسندگان
چکیده
1 Department of Molecular and Comparative Pathobiology, The Johns Hopkins University School of Medicine, 733 N. Broadway, Edward D. Miller Research Building, Baltimore, MD 21205, USA; E-Mails: [email protected] (J.M.S.); [email protected] (J.E.C.) 2 Department of Neurology, The Johns Hopkins University School of Medicine, 733 N. Broadway, Edward D. Miller Research Building, Baltimore, MD 21205, USA 3 Department of Pathology, The Johns Hopkins University School of Medicine, 733 N. Broadway, Edward D. Miller Research Building, Baltimore, MD 21205, USA
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miRNA Profiles of Monocyte-Lineage Cells Are Consistent with Complicated Roles in HIV-1 Restriction
Long-lived HIV-1 reservoirs include tissue macrophages. Monocyte-derived macrophages are more susceptible to infection and more permissive to HIV-1 replication than monocytes for reasons that may include the effects of different populations of miRNAs in these two cell classes. Specifically, miRs-28-3p, -150, -223, -198, and -382 exert direct or indirect negative effects on HIV-1 and are reporte...
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